D(+)-Galactosamine-¹³C hydrochloride  (Synonyms: D-Galactosamine-¹³C (hydrochloride))

D(+)-Galactosamine-¹³C (hydrochloride) is the ¹³C labeled D(+)-Galactosamine hydrochloride. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

216.62

C₅¹³CH₁₄ClNO₅

478518-54-6

1772-03-8

OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](N)[13CH]=O.Cl

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Ayhanci A, et al. Protective effects of ellagic acid in D-galactosamine-induced kidney damage in rats. Cytotechnology. 2016;68(5):1763-1770. ;Okumura A, et al. Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derive  [Content Brief]