2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Thrombin
  4. Dabigatran etexilate-d13

Dabigatran etexilate-d13 is the deuterium labeled Dabigatran etexilate. Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran. Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1].

For research use only. We do not sell to patients.

Dabigatran etexilate-d<sub>13</sub> Chemical Structure

Dabigatran etexilate-d13 Chemical Structure

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1 mg USD 290 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Dabigatran etexilate-d13:

Dabigatran etexilate-d13 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Dabigatran etexilate-d13 is the deuterium labeled Dabigatran etexilate. Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran. Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dabigatran etexilate-d13 Related Antibodies
Molecular Weight

640.81

Formula

C34H28D13N7O5
Unlabeled CAS

211915-06-9
Appearance

Solid

Color

White to off-white

SMILES

O=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C(NC(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)=N)C=C4)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (156.05 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 100 mg/mL (156.05 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5605 mL 7.8026 mL 15.6052 mL
5 mM 0.3121 mL 1.5605 mL 3.1210 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (247 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 1.5605 mL 7.8026 mL 15.6052 mL 39.0131 mL
5 mM 0.3121 mL 1.5605 mL 3.1210 mL 7.8026 mL
10 mM 0.1561 mL 0.7803 mL 1.5605 mL 3.9013 mL
15 mM 0.1040 mL 0.5202 mL 1.0403 mL 2.6009 mL
20 mM 0.0780 mL 0.3901 mL 0.7803 mL 1.9507 mL
25 mM 0.0624 mL 0.3121 mL 0.6242 mL 1.5605 mL
30 mM 0.0520 mL 0.2601 mL 0.5202 mL 1.3004 mL
40 mM 0.0390 mL 0.1951 mL 0.3901 mL 0.9753 mL
50 mM 0.0312 mL 0.1561 mL 0.3121 mL 0.7803 mL
60 mM 0.0260 mL 0.1300 mL 0.2601 mL 0.6502 mL
80 mM 0.0195 mL 0.0975 mL 0.1951 mL 0.4877 mL
100 mM 0.0156 mL 0.0780 mL 0.1561 mL 0.3901 mL
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Dabigatran etexilate-d13 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dabigatran etexilate-d13Isotope-Labeled CompoundsThrombinInhibitorinhibitorinhibit

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