1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease
  3. Dansyl-Glu-Gly-Arg-Chloromethylketone TFA

Dansyl-Glu-Gly-Arg-Chloromethylketone TFA 

Cat. No.: HY-P4243A Purity: 98.45%
SDS COA Handling Instructions Technical Support

Dansyl-Glu-Gly-Arg-Chloromethylketone TFA is a protease inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone TFA inhibits activated porcine factor IX.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Dansyl-Glu-Gly-Arg-Chloromethylketone TFA Chemical Structure

Dansyl-Glu-Gly-Arg-Chloromethylketone TFA Chemical Structure

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Description

Dansyl-Glu-Gly-Arg-Chloromethylketone TFA is a protease inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone TFA inhibits activated porcine factor IX[1].

Molecular Weight

740.15

Formula

C28H37ClF3N7O9S

Appearance

Solid

Color

Light yellow to yellow

Sequence

{Dansyl}-Glu-Gly-Arg-{CMK}

Sequence Shortening

{Dansyl}-EGR-{CMK}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (67.55 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3511 mL 6.7554 mL 13.5108 mL
5 mM 0.2702 mL 1.3511 mL 2.7022 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.3511 mL 6.7554 mL 13.5108 mL 33.7769 mL
5 mM 0.2702 mL 1.3511 mL 2.7022 mL 6.7554 mL
10 mM 0.1351 mL 0.6755 mL 1.3511 mL 3.3777 mL
15 mM 0.0901 mL 0.4504 mL 0.9007 mL 2.2518 mL
20 mM 0.0676 mL 0.3378 mL 0.6755 mL 1.6888 mL
25 mM 0.0540 mL 0.2702 mL 0.5404 mL 1.3511 mL
30 mM 0.0450 mL 0.2252 mL 0.4504 mL 1.1259 mL
40 mM 0.0338 mL 0.1689 mL 0.3378 mL 0.8444 mL
50 mM 0.0270 mL 0.1351 mL 0.2702 mL 0.6755 mL
60 mM 0.0225 mL 0.1126 mL 0.2252 mL 0.5629 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dansyl-Glu-Gly-Arg-Chloromethylketone TFA Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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