2. Protein Tyrosine Kinase/RTK Apoptosis Autophagy
  3. Bcr-Abl Src Apoptosis Autophagy
  4. Dasatinib-d8

Dasatinib-d8  (Synonyms: BMS-354825-d8)

Cat. No.: HY-10181S Purity: 98.17%
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Dasatinib-d8 is a deuterium labeled Dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.

For research use only. We do not sell to patients.

Dasatinib-d<sub>8</sub> Chemical Structure

Dasatinib-d8 Chemical Structure

CAS No. : 1132093-70-9

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500 μg USD 110 In-stock
1 mg USD 205 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Dasatinib-d8:

Dasatinib-d8 Related Antibodies

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Description

Dasatinib-d8 is a deuterium labeled Dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.

Molecular Weight

496.05

Formula

C22H18D8ClN7O2S
CAS No.
Unlabeled CAS

302962-49-8
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CN=C(NC2=NC(C)=NC(N3C([2H])([2H])C([2H])([2H])N(CCO)C([2H])([2H])C3([2H])[2H])=C2)S1)NC4=C(C)C=CC=C4Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (503.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 250 mg/mL (503.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0159 mL 10.0796 mL 20.1593 mL
5 mM 0.4032 mL 2.0159 mL 4.0319 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.0159 mL 10.0796 mL 20.1593 mL 50.3981 mL
5 mM 0.4032 mL 2.0159 mL 4.0319 mL 10.0796 mL
10 mM 0.2016 mL 1.0080 mL 2.0159 mL 5.0398 mL
15 mM 0.1344 mL 0.6720 mL 1.3440 mL 3.3599 mL
20 mM 0.1008 mL 0.5040 mL 1.0080 mL 2.5199 mL
25 mM 0.0806 mL 0.4032 mL 0.8064 mL 2.0159 mL
30 mM 0.0672 mL 0.3360 mL 0.6720 mL 1.6799 mL
40 mM 0.0504 mL 0.2520 mL 0.5040 mL 1.2600 mL
50 mM 0.0403 mL 0.2016 mL 0.4032 mL 1.0080 mL
60 mM 0.0336 mL 0.1680 mL 0.3360 mL 0.8400 mL
80 mM 0.0252 mL 0.1260 mL 0.2520 mL 0.6300 mL
100 mM 0.0202 mL 0.1008 mL 0.2016 mL 0.5040 mL
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Dasatinib-d8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dasatinib-d81132093-70-9BMS-354825-d8Bcr-AblSrcApoptosisAutophagydeuteriumlabeledDasatinibInhibitorinhibitorinhibit

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