Daurichromenic acid (Synonyms: (+)-Daurichromenic acid)

Cat. No.: HY-N3692: FAQs
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Daurichromenic acid is a chromene, which can be isolated from the leaves and twigs of Rhododendron dauricum. Daurichromenic acid has potent anti-HIV activity with an EC₅₀ value of 0.00567 μg/mL.

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Daurichromenic acid Chemical Structure

CAS No. : 82003-90-5

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Description

Cellular Effect

Cell Line	Type	Value	Description	References
H9	EC₅₀	0.015 μM Compound: 123	Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA	[PMID: 20187635]
H9	IC₅₀	21.1 mg/mL Compound: 64	Cytotoxicity against human H9 cells by Coulter counter method Cytotoxicity against human H9 cells by Coulter counter method	[PMID: 27494166]

Molecular Weight

370.48

Formula

C₂₃H₃₀O₄

CAS No.

82003-90-5

SMILES

OC1=C2C(O[C@](C)(C=C2)CC/C=C(C)/CC/C=C(C)/C)=CC(C)=C1C(O)=O

Structure Classification

Initial Source

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kashiwada Y, et al. Isolation of rhododaurichromanic acid B and the anti-HIV principles rhododaurichromanic acid A and rhododaurichromenic acid from Rhododendron dauricum[J]. Tetrahedron, 2001, 57(8): 1559-1563.

Daurichromenic acid Related Classifications

Infection

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Daurichromenic acid82003-90-5(+)-Daurichromenic acidHIVHuman immunodeficiency viruschromeneRhododendron dauricumanti-HIVInhibitorinhibitorinhibit

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