2. Antibody-drug Conjugate/ADC Related
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  4. DBCO-PEG2-NHS ester

DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only.

For research use only. We do not sell to patients.

DBCO-PEG2-NHS ester Chemical Structure

DBCO-PEG2-NHS ester Chemical Structure

CAS No. : 2585653-12-7

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Based on 1 publication(s) in Google Scholar

DBCO-PEG2-NHS ester Related Antibodies

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Description

DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only[1].

Molecular Weight

561.58

Formula

C30H31N3O8
CAS No.
Appearance

Oil

Color

Yellow to brown

SMILES

O=C(CCOCCOCCNC(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O)ON4C(CCC4=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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DBCO-PEG2-NHS ester Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DBCO-PEG2-NHS ester2585653-12-7ADC LinkerAntibody-drug conjugates linkerclick chemistryhigh yieldhigh specificitysimplicitybindingInhibitorinhibitorinhibit

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