2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. DBCO-PEG4-Val-Ala-PAB

DBCO-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility.

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DBCO-PEG4-Val-Ala-PAB Chemical Structure

DBCO-PEG4-Val-Ala-PAB Chemical Structure

CAS No. : 2348405-92-3

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Description

DBCO-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility.

Molecular Weight

827.96

Formula

C45H57N5O10
CAS No.
SMILES

CC([C@@H](C(N[C@H](C(NC1=CC=C(C=C1)CO)=O)C)=O)NC(CCOCCOCCOCCOCCNC(CCC(N2CC3=C(C#CC4=C2C=CC=C4)C=CC=C3)=O)=O)=O)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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DBCO-PEG4-Val-Ala-PAB Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2

Keywords:

DBCO-PEG4-Val-Ala-PAB2348405-92-3ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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