2. Anti-infection Autophagy
  3. Antibiotic Bacterial Autophagy
  4. DCAP

DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux.

For research use only. We do not sell to patients.

DCAP Chemical Structure

DCAP Chemical Structure

CAS No. : 500015-20-3

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5 mg USD 80 In-stock
10 mg USD 130 In-stock
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DCAP Related Antibodies

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Description

DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux[1].

Molecular Weight

413.29

Formula

C19H22Cl2N2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCC(CO)(NCC(O)CN1C2=C(C3=C1C=CC(Cl)=C3)C=C(Cl)C=C2)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 5 mg/mL (12.10 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4196 mL 12.0980 mL 24.1961 mL
5 mM 0.4839 mL 2.4196 mL 4.8392 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4196 mL 12.0980 mL 24.1961 mL 60.4902 mL
5 mM 0.4839 mL 2.4196 mL 4.8392 mL 12.0980 mL
10 mM 0.2420 mL 1.2098 mL 2.4196 mL 6.0490 mL
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DCAP Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DCAP500015-20-3AntibioticBacterialAutophagyantibioticGram-positiveGram-negative bacteriaautophagic fluxInhibitorinhibitorinhibit

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