DCG04 isomer-1 

DCG04 isomer-1 is an isomer of DCG04 (HY-101779). DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates^[1][2].

903.10

C₄₃H₆₆N₈O₁₁S

OC(C=C1)=CC=C1C[C@@H](C(NCCCCCC(N[C@H](C(N)=O)CCCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O)=O)NC([C@H](CC(C)C)NC(C4C(O4)C(OCC)=O)=O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Hillaert U, et al. Receptor-mediated targeting of cathepsins in professional antigen presenting cells [published correction appears in Angew Chem Int Ed Engl. 2009;48(14):2442.. Saragliadis, Anastasios [corrected to Saragliadis, Athanasios]]. Angew Chem Int Ed Engl. 2009;48(9):1629-1632.  [Content Brief]

  [2]. Paulick MG, et al. Development of activity-based probes for cathepsin X. ACS Chem Biol. 2011;6(6):563-572.  [Content Brief]