2. GPCR/G Protein Metabolic Enzyme/Protease MAPK/ERK Pathway
  3. Phosphodiesterase (PDE) Ras
  4. Deltarasin trihydrochloride

Deltarasin is an inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ. Deltarasin can be used in the study of cancer.

For research use only. We do not sell to patients.

Deltarasin trihydrochloride Chemical Structure

Deltarasin trihydrochloride Chemical Structure

CAS No. : 1440898-82-7

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Deltarasin trihydrochloride Related Antibodies

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Description

Deltarasin is an inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ. Deltarasin can be used in the study of cancer.

Cellular Effect
Cell Line Type Value Description References
A549 IC50
6.4 μM
Compound: Deltarasin
Antiproliferative activity against human A549 cells harboring KRAS G12S point mutant after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells harboring KRAS G12S point mutant after 72 hrs by SRB assay
[PMID: 30562696]
Molecular Weight

713.14

Formula

C40H40Cl3N5O
CAS No.
SMILES

C1(CN2C3=CC=CC=C3N=C2C4=CC=C(OC[C@@H](N5C6=CC=CC=C6N=C5C7=CC=CC=C7)C8CCNCC8)C=C4)=CC=CC=C1.Cl.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Deltarasin trihydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Deltarasin trihydrochloride1440898-82-7Phosphodiesterase (PDE)RascancerInhibitorinhibitorinhibit

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