2. Apoptosis Anti-infection Autophagy
  3. Autophagy Bacterial Apoptosis
  4. Demethoxycurcumin-d4

Demethoxycurcumin-d4  (Synonyms: Curcumin II-d4; Desmethoxycurcumin-d4; Monodemethoxycurcumin-d4)

Cat. No.: HY-N0006S1 Purity: 97.77%
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Demethoxycurcumin-d4 is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

For research use only. We do not sell to patients.

Demethoxycurcumin-d<sub>4</sub> Chemical Structure

Demethoxycurcumin-d4 Chemical Structure

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1 mg USD 450 In-stock
5 mg USD 1450 In-stock
10 mg USD 2500 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Demethoxycurcumin-d4:

Demethoxycurcumin-d4 Related Antibodies

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  • Purity & Documentation

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Description

Demethoxycurcumin-d4 is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Demethoxycurcumin-d4 Related Antibodies
Molecular Weight

342.38

Formula

C20H14D4O5
Unlabeled CAS

22608-11-3
Appearance

Solid

Color

Orange to red

SMILES

O=C(CC(/C=C/C1=C([2H])C([2H])=C(O)C([2H])=C1[2H])=O)/C=C/C2=CC=C(O)C(OC)=C2
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (292.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 100 mg/mL (292.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9207 mL 14.6037 mL 29.2073 mL
5 mM 0.5841 mL 2.9207 mL 5.8415 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.9207 mL 14.6037 mL 29.2073 mL 73.0183 mL
5 mM 0.5841 mL 2.9207 mL 5.8415 mL 14.6037 mL
10 mM 0.2921 mL 1.4604 mL 2.9207 mL 7.3018 mL
15 mM 0.1947 mL 0.9736 mL 1.9472 mL 4.8679 mL
20 mM 0.1460 mL 0.7302 mL 1.4604 mL 3.6509 mL
25 mM 0.1168 mL 0.5841 mL 1.1683 mL 2.9207 mL
30 mM 0.0974 mL 0.4868 mL 0.9736 mL 2.4339 mL
40 mM 0.0730 mL 0.3651 mL 0.7302 mL 1.8255 mL
50 mM 0.0584 mL 0.2921 mL 0.5841 mL 1.4604 mL
60 mM 0.0487 mL 0.2434 mL 0.4868 mL 1.2170 mL
80 mM 0.0365 mL 0.1825 mL 0.3651 mL 0.9127 mL
100 mM 0.0292 mL 0.1460 mL 0.2921 mL 0.7302 mL
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Demethoxycurcumin-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Demethoxycurcumin-d4Curcumin II-d4Desmethoxycurcumin-d4Monodemethoxycurcumin-d4AutophagyBacterialApoptosisInhibitorinhibitorinhibit

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