2. Anti-infection Cell Cycle/DNA Damage
  3. Dengue virus Flavivirus HIV DNA/RNA Synthesis
  4. DENV-IN-5

DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM.

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DENV-IN-5 Chemical Structure

DENV-IN-5 Chemical Structure

CAS No. : 2375781-06-7

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Based on 1 publication(s) in Google Scholar

DENV-IN-5 Related Antibodies

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Description

DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM[1].

IC50 & Target

HIV (IIIB)

0.1512 μM (EC50)

DENV-I

1.47 μM (EC50)

DENV-III

7.08 μM (EC50)

DENV-IV

8.91 μM (EC50)

DENV-II

9.23 μM (EC50)

Molecular Weight

478.99

Formula

C23H25ClF2N4OS
CAS No.
SMILES

CCC1=C(N=C(NC1=O)SCC2=NNC(C3=CC(F)=C(C=C3)F)=C2Cl)CC4CCCCC4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DENV-IN-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DENV-IN-52375781-06-7Dengue virusFlavivirusHIVDNA/RNA SynthesisDENVHuman immunodeficiency virusHIV-1IIIBInhibitorinhibitorinhibit

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