2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Deoxycorticosterone-d8

Deoxycorticosterone-d8 is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor[1][2].

For research use only. We do not sell to patients.

Deoxycorticosterone-d<sub>8</sub> Chemical Structure

Deoxycorticosterone-d8 Chemical Structure

CAS No. : 55487-63-3

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Based on 1 publication(s) in Google Scholar

Other Forms of Deoxycorticosterone-d8:

Deoxycorticosterone-d8 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Deoxycorticosterone-d8 is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Deoxycorticosterone-d8 Related Antibodies
Molecular Weight

338.51

Formula

C21H22D8O3
CAS No.
Unlabeled CAS

64-85-7
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(C(C3)([2H])[2H])=C(C(=O)C(C4)([2H])[2H])[2H])(CC1)[H])[H])(CC[C@@]2(C(C(O)([2H])[2H])=O)[2H])[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (738.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 250 mg/mL (738.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9541 mL 14.7706 mL 29.5412 mL
5 mM 0.5908 mL 2.9541 mL 5.9082 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 97.44%

COA (255 KB) HNMR (301 KB) RP-HPLC (1065 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.9541 mL 14.7706 mL 29.5412 mL 73.8531 mL
5 mM 0.5908 mL 2.9541 mL 5.9082 mL 14.7706 mL
10 mM 0.2954 mL 1.4771 mL 2.9541 mL 7.3853 mL
15 mM 0.1969 mL 0.9847 mL 1.9694 mL 4.9235 mL
20 mM 0.1477 mL 0.7385 mL 1.4771 mL 3.6927 mL
25 mM 0.1182 mL 0.5908 mL 1.1816 mL 2.9541 mL
30 mM 0.0985 mL 0.4924 mL 0.9847 mL 2.4618 mL
40 mM 0.0739 mL 0.3693 mL 0.7385 mL 1.8463 mL
50 mM 0.0591 mL 0.2954 mL 0.5908 mL 1.4771 mL
60 mM 0.0492 mL 0.2462 mL 0.4924 mL 1.2309 mL
80 mM 0.0369 mL 0.1846 mL 0.3693 mL 0.9232 mL
100 mM 0.0295 mL 0.1477 mL 0.2954 mL 0.7385 mL
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Deoxycorticosterone-d8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Deoxycorticosterone-d855487-63-3Endogenous MetaboliteInhibitorinhibitorinhibit

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