Dermaseptin-S1

Cat. No.: HY-P5594 Purity: 97.12%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Dermaseptin-S1 is an antimicrobial peptide derived from frog skin against filamentous fungi.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Dermaseptin-S1 Chemical Structure

CAS No. : 136033-70-0

Size	Price	Stock	Quantity
1 mg	USD 130	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 325	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 485	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Biological Activity
Purity & Documentation
References
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Description

Dermaseptin-S1 is an antimicrobial peptide derived from frog skin against filamentous fungi^[1].

Molecular Weight

3455.06

Formula

C₁₅₂H₂₅₇N₄₃O₄₄S₂

CAS No.

136033-70-0

Appearance

Solid

Color

White to off-white

Sequence

Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln

Sequence Shortening

ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 12.5 mg/mL (3.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.2894 mL	1.4472 mL	2.8943 mL
5 mM	---	---	---
10 mM	---	---	---

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.12%

Select Batch:

Data Sheet (267 KB) SDS (252 KB)

COA (243 KB) RP-HPLC (110 KB) MS (203 KB)

Handling Instructions (2659 KB)

References

[1]. Mor A, et al. The vertebrate peptide antibiotics dermaseptins have overlapping structural features but target specific microorganisms. J Biol Chem. 1994 Dec 16;269(50):31635-41. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO

1 mM

0.2894 mL

1.4472 mL

2.8943 mL

7.2358 mL

Dermaseptin-S1 Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dermaseptin-S1136033-70-0Fungalantimicrobial peptidefilamentous fungiInhibitorinhibitorinhibit

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