[Des-Pro2]-Bradykinin

Cat. No.: HY-P2828 Purity: 99.68%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

[Des-Pro2]-Bradykinin is a protease inhibitor. [Des-Pro2]-Bradykinin prevents the degradation of methionine enkephalin.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

[Des-Pro2]-Bradykinin Chemical Structure

CAS No. : 80943-05-1

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

[Des-Pro2]-Bradykinin is a protease inhibitor. [Des-Pro2]-Bradykinin prevents the degradation of methionine enkephalin^[1].

Molecular Weight

963.09

Formula

C₄₅H₆₆N₁₄O₁₀

CAS No.

80943-05-1

Appearance

Solid

Color

White to off-white

Sequence

Arg-Pro-Gly-Phe-Ser-Pro-Phe-Arg

Sequence Shortening

RPGFSPFR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Purity & Documentation

Purity: 99.68%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (258 KB) RP-HPLC (110 KB) MS (205 KB) Elemental Analysis Report (117 KB)

Handling Instructions (2659 KB)

References

[1]. Koide S, et al. Endogenous methionine enkephalin may play an anticonvulsant role in the seizure-susceptible El mouse. Neurochem Res. 1993 Dec;18(12):1259-62. [Content Brief]

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.0383 mL	5.1916 mL	10.3832 mL	25.9581 mL
	5 mM	0.2077 mL	1.0383 mL	2.0766 mL	5.1916 mL
	10 mM	0.1038 mL	0.5192 mL	1.0383 mL	2.5958 mL
	15 mM	0.0692 mL	0.3461 mL	0.6922 mL	1.7305 mL
	20 mM	0.0519 mL	0.2596 mL	0.5192 mL	1.2979 mL
	25 mM	0.0415 mL	0.2077 mL	0.4153 mL	1.0383 mL
	30 mM	0.0346 mL	0.1731 mL	0.3461 mL	0.8653 mL
	40 mM	0.0260 mL	0.1298 mL	0.2596 mL	0.6490 mL
	50 mM	0.0208 mL	0.1038 mL	0.2077 mL	0.5192 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.