DEX-maleimide

Cat. No.: HY-46225 Purity: 99.80%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

DEX-maleimide is a coupling agent that can be used to synthesize conjugates containing single-domain antibodies (VHH) conjugated with antigens and anti-inflammatory agents. DEX-maleimide can be used for research on autoimmune diseases.

For research use only. We do not sell to patients.

DEX-maleimide Chemical Structure

CAS No. : 2754462-35-4

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
10 mg	USD 340	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 680	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1100	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 1800	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Purity & Documentation
References
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Description

Molecular Weight

557.61

Formula

C₂₉H₃₆FN₃O₇

CAS No.

2754462-35-4

Appearance

Solid

Color

White to yellow

SMILES

C[C@]([C@](O)1/C(CO)=N/NC(CCN(C2=O)C(C=C2)=O)=O)(C[C@@H]3O)[C@](C[C@H]1C)([H])[C@@](CCC4=CC5=O)([H])[C@]3([C@]4(C=C5)C)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (179.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7934 mL	8.9668 mL	17.9337 mL
5 mM	0.3587 mL	1.7934 mL	3.5867 mL
10 mM	0.1793 mL	0.8967 mL	1.7934 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.80%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (254 KB) HNMR (294 KB) RP-HPLC (257 KB) LCMS (145 KB)

Handling Instructions (2659 KB)

References

[1]. Pishesha, et al. Nanobody (VHH) conjugates and uses thereof. U.S., WO2021247688 A2. 2023-07-27.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.7934 mL	8.9668 mL	17.9337 mL	44.8342 mL
	5 mM	0.3587 mL	1.7934 mL	3.5867 mL	8.9668 mL
	10 mM	0.1793 mL	0.8967 mL	1.7934 mL	4.4834 mL
	15 mM	0.1196 mL	0.5978 mL	1.1956 mL	2.9889 mL
	20 mM	0.0897 mL	0.4483 mL	0.8967 mL	2.2417 mL
	25 mM	0.0717 mL	0.3587 mL	0.7173 mL	1.7934 mL
	30 mM	0.0598 mL	0.2989 mL	0.5978 mL	1.4945 mL
	40 mM	0.0448 mL	0.2242 mL	0.4483 mL	1.1209 mL
	50 mM	0.0359 mL	0.1793 mL	0.3587 mL	0.8967 mL
	60 mM	0.0299 mL	0.1494 mL	0.2989 mL	0.7472 mL
	80 mM	0.0224 mL	0.1121 mL	0.2242 mL	0.5604 mL
	100 mM	0.0179 mL	0.0897 mL	0.1793 mL	0.4483 mL

DEX-maleimide Related Classifications

Inflammation/Immunology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DEX-maleimide2754462-35-4Othersimmunosuppressionautoimmune diseasesInhibitorinhibitorinhibit

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