1. PROTAC Immunology/Inflammation
  2. Ligands for Target Protein for PROTAC STING
  3. diABZI-V/C-Mal

diABZI-V/C-Mal is a STING agonist.

For research use only. We do not sell to patients.

diABZI-V/C-Mal Chemical Structure

diABZI-V/C-Mal Chemical Structure

CAS No. : 3035557-55-9

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Description

diABZI-V/C-Mal is a STING agonist.

Molecular Weight

1378.49

Formula

C67H83N19O14

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C5=C(OCCCNC(OCC6=CC=C(C=C6)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)=O)C=C(C(N)=O)C=C5N=C4NC(C8=CC(C)=NN8CC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (72.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7254 mL 3.6272 mL 7.2543 mL
5 mM 0.1451 mL 0.7254 mL 1.4509 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7254 mL 3.6272 mL 7.2543 mL 18.1358 mL
5 mM 0.1451 mL 0.7254 mL 1.4509 mL 3.6272 mL
10 mM 0.0725 mL 0.3627 mL 0.7254 mL 1.8136 mL
15 mM 0.0484 mL 0.2418 mL 0.4836 mL 1.2091 mL
20 mM 0.0363 mL 0.1814 mL 0.3627 mL 0.9068 mL
25 mM 0.0290 mL 0.1451 mL 0.2902 mL 0.7254 mL
30 mM 0.0242 mL 0.1209 mL 0.2418 mL 0.6045 mL
40 mM 0.0181 mL 0.0907 mL 0.1814 mL 0.4534 mL
50 mM 0.0145 mL 0.0725 mL 0.1451 mL 0.3627 mL
60 mM 0.0121 mL 0.0605 mL 0.1209 mL 0.3023 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
diABZI-V/C-Mal
Cat. No.:
HY-164278
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