1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Diadenosine pentaphosphate pentasodium

Diadenosine pentaphosphate pentasodium 

Cat. No.: HY-113273A Purity: 97%
SDS COA Handling Instructions

Diadenosine pentaphosphate pentasodium is an endogenous vasoactive purine dinucleotide which has been isolated from thrombocytes. Diadenosine polyphosphates (ApnA, n=2–7) have been identified as constituents of secretory vesicles such as in platelets, chromaffin cells, Torpedo synaptic terminals and brain synaptosomes.

For research use only. We do not sell to patients.

Diadenosine pentaphosphate pentasodium Chemical Structure

Diadenosine pentaphosphate pentasodium Chemical Structure

CAS No. : 4097-04-5

Size Price Stock Quantity
1 mg USD 145 In-stock
5 mg USD 430 In-stock
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50 mg   Get quote  

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Description

Diadenosine pentaphosphate pentasodium is an endogenous vasoactive purine dinucleotide which has been isolated from thrombocytes. Diadenosine polyphosphates (ApnA, n=2–7) have been identified as constituents of secretory vesicles such as in platelets, chromaffin cells, Torpedo synaptic terminals and brain synaptosomes[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

1026.28

Formula

C20H24N10Na5O22P5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]1COP(OP(OP(OP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C6=NC=NC(N)=C6N=C5)O4)(O[Na])=O)(O[Na])=O)(O[Na])=O)(O[Na])=O)(O[Na])=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (97.44 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9744 mL 4.8720 mL 9.7439 mL
5 mM 0.1949 mL 0.9744 mL 1.9488 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥97.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.9744 mL 4.8720 mL 9.7439 mL 24.3598 mL
5 mM 0.1949 mL 0.9744 mL 1.9488 mL 4.8720 mL
10 mM 0.0974 mL 0.4872 mL 0.9744 mL 2.4360 mL
15 mM 0.0650 mL 0.3248 mL 0.6496 mL 1.6240 mL
20 mM 0.0487 mL 0.2436 mL 0.4872 mL 1.2180 mL
25 mM 0.0390 mL 0.1949 mL 0.3898 mL 0.9744 mL
30 mM 0.0325 mL 0.1624 mL 0.3248 mL 0.8120 mL
40 mM 0.0244 mL 0.1218 mL 0.2436 mL 0.6090 mL
50 mM 0.0195 mL 0.0974 mL 0.1949 mL 0.4872 mL
60 mM 0.0162 mL 0.0812 mL 0.1624 mL 0.4060 mL
80 mM 0.0122 mL 0.0609 mL 0.1218 mL 0.3045 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Diadenosine pentaphosphate pentasodium
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