2. Anti-infection
  3. Bacterial
  4. Diethylamine NONOate diethylammonium salt

Diethylamine NONOate diethylammonium salt  (Synonyms: DEA NONOate diethylamine)

Cat. No.: HY-131925 Purity: ≥98.0%
SDS COA Handling Instructions

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Diethylamine NONOate (DEA NONOate, diethylammonium salt) is a nitric oxide donor. Diethylamine NONOate is a potent antimicrobial agent, which can inhibit Escherichia coli growth. Diethylamine NONOate also can enhance preservation of the donor rat heart.

For research use only. We do not sell to patients.

Diethylamine NONOate diethylammonium salt Chemical Structure

Diethylamine NONOate diethylammonium salt Chemical Structure

CAS No. : 372965-00-9

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5 mg USD 30 In-stock
10 mg USD 48 In-stock
25 mg USD 95 In-stock
50 mg USD 153 In-stock
100 mg USD 245 In-stock
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Based on 1 publication(s) in Google Scholar

Diethylamine NONOate diethylammonium salt Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Diethylamine NONOate (DEA NONOate, diethylammonium salt) is a nitric oxide donor. Diethylamine NONOate is a potent antimicrobial agent, which can inhibit Escherichia coli growth. Diethylamine NONOate also can enhance preservation of the donor rat heart[1][2].

In Vitro

Diethylamine NONOate (8 and 65 mM; 0-20 h) diethylammonium salt shows the greatest inhibitory effect on E. coli growth at a dose of 65 mM for 20 h, resulting in a 99.9% reduction in E. coli[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Diethylamine NONOate diethylammonium salt Related Antibodies
In Vivo

Diethylamine NONOate (0.1 micromol/L; infused into the coronary circulation; 6 or 12 h) diethylammonium salt enhances the protection of coronary blood flow and cardiac function in isolated rat hearts after storage at 2-3 °C for 12 h[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

206.29

Formula

C8H22N4O2
CAS No.
Appearance

Solid

Color

White to light brown

SMILES

CCNCC.O=NN(O)N(CC)CC
Shipping

Shipping with dry ice.
Storage

-80°C
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (605.94 mM; Need ultrasonic)

DMSO : ≥ 100 mg/mL (484.75 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8475 mL 24.2377 mL 48.4754 mL
5 mM 0.9695 mL 4.8475 mL 9.6951 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

SDS (555 KB)

COA (249 KB) Elemental Analysis Report (107 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.8475 mL 24.2377 mL 48.4754 mL 121.1886 mL
5 mM 0.9695 mL 4.8475 mL 9.6951 mL 24.2377 mL
10 mM 0.4848 mL 2.4238 mL 4.8475 mL 12.1189 mL
15 mM 0.3232 mL 1.6158 mL 3.2317 mL 8.0792 mL
20 mM 0.2424 mL 1.2119 mL 2.4238 mL 6.0594 mL
25 mM 0.1939 mL 0.9695 mL 1.9390 mL 4.8475 mL
30 mM 0.1616 mL 0.8079 mL 1.6158 mL 4.0396 mL
40 mM 0.1212 mL 0.6059 mL 1.2119 mL 3.0297 mL
50 mM 0.0970 mL 0.4848 mL 0.9695 mL 2.4238 mL
60 mM 0.0808 mL 0.4040 mL 0.8079 mL 2.0198 mL
80 mM 0.0606 mL 0.3030 mL 0.6059 mL 1.5149 mL
100 mM 0.0485 mL 0.2424 mL 0.4848 mL 1.2119 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Diethylamine NONOate diethylammonium salt Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Diethylamine NONOate diethylammonium372965-00-9DEA NONOateBacterialNO donorAntiviral agentAntimicrobial agentSARS-CoV-2Escherichia coliInhibitorinhibitorinhibit

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