Diflubenzuron-d₄ 

Diflubenzuron-d₄ is the deuterium labeled Diflubenzuron[1]. Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities[2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

314.71

C₁₄H₅D₄ClF₂N₂O₂

1219795-45-5

35367-38-5

ClC(C([2H])=C1[2H])=C([2H])C([2H])=C1NC(NC(C2=C(C=CC=C2F)F)=O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Ker RF. Investigation of locust cuticle using the insecticide diflubenzuron. J Insect Physiol. 1977;23(1):39-48.  [Content Brief]

  [3]. Arnold C. Grosscurt, et al. Diflubenzuron: Some aspects of its ovicidal and larvicidal mode of action and an evaluation of its practical possibilities. Pest Management Science.