1. Diflubenzuron

Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities.

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Diflubenzuron Chemical Structure

Diflubenzuron Chemical Structure

CAS No. : 35367-38-5

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Description

Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities[1][2].

Cellular Effect
Cell Line Type Value Description References
CCRF-CEM IC50
> 20 μg/mL
Compound: 140
Concentration required to inhibit growth of CCRF-CEM cells in culture for 72 hr to 50% of control growth
Concentration required to inhibit growth of CCRF-CEM cells in culture for 72 hr to 50% of control growth
[PMID: 2391684]
Molecular Weight

310.68

Formula

C14H9ClF2N2O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC(NC1=CC=C(Cl)C=C1)=O)C2=C(F)C=CC=C2F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

RT, sealed storage, away from moisture and light

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 175 mg/mL (563.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2187 mL 16.0937 mL 32.1875 mL
5 mM 0.6437 mL 3.2187 mL 6.4375 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2187 mL 16.0937 mL 32.1875 mL 80.4687 mL
5 mM 0.6437 mL 3.2187 mL 6.4375 mL 16.0937 mL
10 mM 0.3219 mL 1.6094 mL 3.2187 mL 8.0469 mL
15 mM 0.2146 mL 1.0729 mL 2.1458 mL 5.3646 mL
20 mM 0.1609 mL 0.8047 mL 1.6094 mL 4.0234 mL
25 mM 0.1287 mL 0.6437 mL 1.2875 mL 3.2187 mL
30 mM 0.1073 mL 0.5365 mL 1.0729 mL 2.6823 mL
40 mM 0.0805 mL 0.4023 mL 0.8047 mL 2.0117 mL
50 mM 0.0644 mL 0.3219 mL 0.6437 mL 1.6094 mL
60 mM 0.0536 mL 0.2682 mL 0.5365 mL 1.3411 mL
80 mM 0.0402 mL 0.2012 mL 0.4023 mL 1.0059 mL
100 mM 0.0322 mL 0.1609 mL 0.3219 mL 0.8047 mL
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Diflubenzuron Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Diflubenzuron
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HY-B1973
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