Dihexyl phthalate-3,4,5,6-d₄

Cat. No.: HY-W011215S Purity: 98.20%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

Dihexyl phthalate-3,4,5,6-d₄ is the deuterium labeled Dihexyl phthalate-3,4,5,6. Dihexyl phthalate (HY-W011215) is one of the commonly used phthalate esters in various plastics and consumer products. Dihexyl phthalate is classified as a priority pollutant and an endocrine disruptor. Dihexyl phthalate can induce reactive oxygen species (ROS) accumulation, promote inflammation, and lead to significant increases in apoptosis and inflammation-related gene expression levels. Dihexyl phthalate can cause testicular atrophy and is a reproductive toxicant.

For research use only. We do not sell to patients.

Dihexyl phthalate-3,4,5,6-d<sub>4</sub> Chemical Structure

Dihexyl phthalate-3,4,5,6-d₄ Chemical Structure

CAS No. : 1015854-55-3

Size	Stock	Quantity
5 mg	Get quote 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
10 mg	Get quote 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Other Forms of Dihexyl phthalate-3,4,5,6-d₄:

Dihexyl phthalate Get quote

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

338.47

Formula

C₂₀H₂₆D₄O₄

CAS No.

1015854-55-3

Unlabeled CAS

84-75-3

Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCCCCOC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(OCCCCCC)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (295.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9545 mL	14.7724 mL	29.5447 mL
5 mM	0.5909 mL	2.9545 mL	5.9089 mL
10 mM	0.2954 mL	1.4772 mL	2.9545 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.20%

Select Batch:

Data Sheet (273 KB) SDS (393 KB)

COA (249 KB) HNMR (248 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Kim YH, et al. Enhanced degradation and toxicity reduction of dihexyl phthalate by Fusarium oxysporum f. sp. pisi cutinase. J Appl Microbiol. 2007 Jan;102(1):221-8. [Content Brief]

[2]. Song D, et al. Combining metabolomics with bioanalysis methods to investigate the potential toxicity of dihexyl phthalate[J]. Environmental toxicology, 2021, 36(2): 213-222. [Content Brief]

[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.9545 mL	14.7724 mL	29.5447 mL	73.8618 mL
	5 mM	0.5909 mL	2.9545 mL	5.9089 mL	14.7724 mL
	10 mM	0.2954 mL	1.4772 mL	2.9545 mL	7.3862 mL
	15 mM	0.1970 mL	0.9848 mL	1.9696 mL	4.9241 mL
	20 mM	0.1477 mL	0.7386 mL	1.4772 mL	3.6931 mL
	25 mM	0.1182 mL	0.5909 mL	1.1818 mL	2.9545 mL
	30 mM	0.0985 mL	0.4924 mL	0.9848 mL	2.4621 mL
	40 mM	0.0739 mL	0.3693 mL	0.7386 mL	1.8465 mL
	50 mM	0.0591 mL	0.2954 mL	0.5909 mL	1.4772 mL
	60 mM	0.0492 mL	0.2462 mL	0.4924 mL	1.2310 mL
	80 mM	0.0369 mL	0.1847 mL	0.3693 mL	0.9233 mL
	100 mM	0.0295 mL	0.1477 mL	0.2954 mL	0.7386 mL