2. Neuronal Signaling GPCR/G Protein Metabolic Enzyme/Protease
  3. Cannabinoid Receptor Endogenous Metabolite
  4. Dihomo-γ-Linolenoyl Ethanolamide

Dihomo-γ-Linolenoyl Ethanolamide, an endocannabinoid, is a cannabinoid (CB) receptor agonist with Kis of 857 nM and 598 nM for human recombinant CB1 and CB2 receptors, respectively.

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Dihomo-γ-Linolenoyl Ethanolamide Chemical Structure

Dihomo-γ-Linolenoyl Ethanolamide Chemical Structure

CAS No. : 150314-34-4

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Dihomo-γ-Linolenoyl Ethanolamide Related Antibodies

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Description

Dihomo-γ-Linolenoyl Ethanolamide, an endocannabinoid, is a cannabinoid (CB) receptor agonist with Kis of 857 nM and 598 nM for human recombinant CB1 and CB2 receptors, respectively[1].

IC50 & Target[1]

hCB1-R

857 nM (Ki)

hCB2-R

598 nM (Ki)

Cellular Effect
Cell Line Type Value Description References
RBL-2H3 IC50
> 50 μM
Compound: 13
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2
[PMID: 31618024]
Molecular Weight

349.55

Formula

C22H39NO2
CAS No.
SMILES

CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(NCCO)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Dihomo-γ-Linolenoyl Ethanolamide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dihomo-γ-Linolenoyl Ethanolamide150314-34-4Cannabinoid ReceptorEndogenous MetaboliteCB1CB2endocannabinoidInhibitorinhibitorinhibit

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