2. Neuronal Signaling
  3. Amyloid-β
  4. Dihydrochalcone

Dihydrochalcone  (Synonyms: 3-Phenylpropiophenone; β-Phenylpropiophenone)

Cat. No.: HY-114508
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Dihydrochalcone (3-Phenylpropiophenone) is a BBB-penatrable Aβ aggregation inhibitor. Dihydrochalcone destabilizes Aβ17-42 protofibrils by disrupting the β-sheet of β1 region. Dihydrochalcone destabilizes both U-shaped Aβ40/Aβ42 protofibrils and S-shaped Aβ42 protofibrils by binding to the protofibril cavity. Dihydrochalcone is the main component of daemonorops draco tree.

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Dihydrochalcone Chemical Structure

Dihydrochalcone Chemical Structure

CAS No. : 1083-30-3

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Dihydrochalcone Related Antibodies

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Description

Dihydrochalcone (3-Phenylpropiophenone) is a BBB-penatrable Aβ aggregation inhibitor. Dihydrochalcone destabilizes Aβ17-42 protofibrils by disrupting the β-sheet of β1 region. Dihydrochalcone destabilizes both U-shaped Aβ40/Aβ42 protofibrils and S-shaped Aβ42 protofibrils by binding to the protofibril cavity. Dihydrochalcone is the main component of daemonorops draco tree[1].

Molecular Weight

210.27

Formula

C15H14O
CAS No.
Appearance

Solid

SMILES

O=C(CCC1=CC=CC=C1)C2=CC=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation
References
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Dihydrochalcone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dihydrochalcone1083-30-33-Phenylpropiophenone β-PhenylpropiophenoneAmyloid-ββ-amyloid peptideAβAbetaAβ40Aβ42protofibrilsInhibitorinhibitorinhibit

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