Diphenyl Phosphate-d₁₀  (Synonyms: DPhP-d₁₀)

Diphenyl Phosphate-d₁₀ (DPhP-d₁₀) is the deuterium labled Diphenyl Phosphate (HY-W008151). Diphenyl Phosphate inhibits growth and energy metabolism of zebrafish in a sex-specific manner.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

260.25

C₁₂HD₁₀O₄P

1477494-97-5

838-85-7

Solid

White to off-white

[2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1OP(OC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])(O)=O

Room temperature in continental US; may vary elsewhere.

• [1]. Chen Q, et al. Life Cycle Exposure to Environmentally Relevant Concentrations of Diphenyl Phosphate (DPhP) Inhibits Growth and Energy Metabolism of Zebrafish in a Sex-Specific Manner. Environ Sci Technol. 2021 Oct 5;55(19):13122-13131.  [Content Brief]

  [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]