2. Metabolic Enzyme/Protease
  3. Dipeptidyl Peptidase
  4. Diprotin B

Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue.

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Diprotin B Chemical Structure

Diprotin B Chemical Structure

CAS No. : 90614-49-6

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Diprotin B Related Antibodies

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Description

Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue[1][2].

Molecular Weight

327.42

Formula

C16H29N3O4
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

VPL
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (305.42 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0542 mL 15.2709 mL 30.5418 mL
5 mM 0.6108 mL 3.0542 mL 6.1084 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.0542 mL 15.2709 mL 30.5418 mL 76.3545 mL
5 mM 0.6108 mL 3.0542 mL 6.1084 mL 15.2709 mL
10 mM 0.3054 mL 1.5271 mL 3.0542 mL 7.6355 mL
15 mM 0.2036 mL 1.0181 mL 2.0361 mL 5.0903 mL
20 mM 0.1527 mL 0.7635 mL 1.5271 mL 3.8177 mL
25 mM 0.1222 mL 0.6108 mL 1.2217 mL 3.0542 mL
30 mM 0.1018 mL 0.5090 mL 1.0181 mL 2.5452 mL
40 mM 0.0764 mL 0.3818 mL 0.7635 mL 1.9089 mL
50 mM 0.0611 mL 0.3054 mL 0.6108 mL 1.5271 mL
60 mM 0.0509 mL 0.2545 mL 0.5090 mL 1.2726 mL
80 mM 0.0382 mL 0.1909 mL 0.3818 mL 0.9544 mL
100 mM 0.0305 mL 0.1527 mL 0.3054 mL 0.7635 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Diprotin B Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Diprotin B90614-49-6Dipeptidyl PeptidaseDPPdiprotinkinetic artifactpeptidesubstrateInhibitorinhibitorinhibit

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