DMNB-caged-Serine

Name: DMNB-caged-Serine
Brand: MedChemExpress
SKU: HY-136276
Rating: 4.5 (1 reviews)

Cat. No.: HY-136276 Purity: 99.48%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

DMNB-caged-Serine is a photocaged amino acid. DMNB-caged-Serine can be used as a catalytic residue, hydrogen bonding partner or site of post-translational modification. DMNB-caged-Serine can be used for the control of protein phosphorylation.

For research use only. We do not sell to patients.

DMNB-caged-Serine Chemical Structure

CAS No. : 780009-55-4

Size	Price	Stock	Quantity
5 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

When substituted at phosphoserine sites that control nuclear export of Pho4, DMNB-caged-Serine blocks phosphorylation and subsequent export by the receptor Msn5^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

300.26

Formula

C₁₂H₁₆N₂O₇

CAS No.

780009-55-4

Appearance

Solid

Color

Light yellow to light brown

SMILES

N[C@@H](COCC1=CC(OC)=C(OC)C=C1[N+]([O-])=O)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (832.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3304 mL	16.6522 mL	33.3045 mL
5 mM	0.6661 mL	3.3304 mL	6.6609 mL
10 mM	0.3330 mL	1.6652 mL	3.3304 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.48%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (248 KB) HNMR (250 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

References

[1]. Edward A Lemke, et al. Control of protein phosphorylation with a genetically encoded photocaged amino acid. Nat Chem Biol. 2007 Dec;3(12):769-72. [Content Brief]

[2]. Qing Shao, et al. Photoactive molecules for applications in molecular imaging and cell biology. Chem Soc Rev. 2010 Aug;39(8):2835-46. [Content Brief]

[3]. Brieke C, et al. Light-controlled tools. Angew Chem Int Ed Engl. 2012 Aug 20;51(34):8446-76. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3304 mL	16.6522 mL	33.3045 mL	83.2612 mL
	5 mM	0.6661 mL	3.3304 mL	6.6609 mL	16.6522 mL
	10 mM	0.3330 mL	1.6652 mL	3.3304 mL	8.3261 mL
	15 mM	0.2220 mL	1.1101 mL	2.2203 mL	5.5507 mL
	20 mM	0.1665 mL	0.8326 mL	1.6652 mL	4.1631 mL
	25 mM	0.1332 mL	0.6661 mL	1.3322 mL	3.3304 mL
	30 mM	0.1110 mL	0.5551 mL	1.1101 mL	2.7754 mL
	40 mM	0.0833 mL	0.4163 mL	0.8326 mL	2.0815 mL
	50 mM	0.0666 mL	0.3330 mL	0.6661 mL	1.6652 mL
	60 mM	0.0555 mL	0.2775 mL	0.5551 mL	1.3877 mL
	80 mM	0.0416 mL	0.2082 mL	0.4163 mL	1.0408 mL
	100 mM	0.0333 mL	0.1665 mL	0.3330 mL	0.8326 mL