1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite

DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite 

Cat. No.: HY-160428
Handling Instructions

DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite (compound 1B) is a phosphoramidite of 5-Fluoro-2'-deoxycytidine.

For research use only. We do not sell to patients.

DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite Chemical Structure

DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite Chemical Structure

CAS No. : 143774-48-5

Size Price Stock
1 mg USD 113 Ask For Quote & Lead Time
5 mg USD 227 Ask For Quote & Lead Time
10 mg USD 341 Ask For Quote & Lead Time
25 mg USD 683 Ask For Quote & Lead Time
50 mg USD 1025 Ask For Quote & Lead Time
100 mg USD 1538 Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Description

DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite (compound 1B) is a phosphoramidite of 5-Fluoro-2'-deoxycytidine[1].

Molecular Weight

747.79

Formula

C39H47FN5O7P

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(N=C(N)C(F)=C1)N1[C@@H]2O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C2

Shipping

Shipping with dry ice.

Storage

-80°C, protect from light, stored under nitrogen

Solvent & Solubility
In Vitro: 

DMSO : 140 mg/mL (187.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3373 mL 6.6864 mL 13.3727 mL
5 mM 0.2675 mL 1.3373 mL 2.6745 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3373 mL 6.6864 mL 13.3727 mL 33.4318 mL
5 mM 0.2675 mL 1.3373 mL 2.6745 mL 6.6864 mL
10 mM 0.1337 mL 0.6686 mL 1.3373 mL 3.3432 mL
15 mM 0.0892 mL 0.4458 mL 0.8915 mL 2.2288 mL
20 mM 0.0669 mL 0.3343 mL 0.6686 mL 1.6716 mL
25 mM 0.0535 mL 0.2675 mL 0.5349 mL 1.3373 mL
30 mM 0.0446 mL 0.2229 mL 0.4458 mL 1.1144 mL
40 mM 0.0334 mL 0.1672 mL 0.3343 mL 0.8358 mL
50 mM 0.0267 mL 0.1337 mL 0.2675 mL 0.6686 mL
60 mM 0.0223 mL 0.1114 mL 0.2229 mL 0.5572 mL
80 mM 0.0167 mL 0.0836 mL 0.1672 mL 0.4179 mL
100 mM 0.0134 mL 0.0669 mL 0.1337 mL 0.3343 mL
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DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite
Cat. No.:
HY-160428
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