1. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  2. DNA-PK
  3. DNA-PK-IN-14

DNA-PK-IN-14 (compound 78) is a potent, selective DNA-PK inhibitor with an IC50 value of 7.95 nM. DNA-PK-IN-14 has oral activity and has the potential to be a radiosensitizer for cancer treatment.

For research use only. We do not sell to patients.

DNA-PK-IN-14 Chemical Structure

DNA-PK-IN-14 Chemical Structure

CAS No. : 2766001-96-9

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Description

DNA-PK-IN-14 (compound 78) is a potent, selective DNA-PK inhibitor with an IC50 value of 7.95 nM. DNA-PK-IN-14 has oral activity and has the potential to be a radiosensitizer for cancer treatment[1].

Molecular Weight

368.43

Formula

C20H24N4O3

CAS No.
SMILES

O=C(N1C2CCOCC2)N(C)C3=C1C=C(NC4=CC=C(OC)C=C4C)N=C3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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DNA-PK-IN-14
Cat. No.:
HY-162692
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