1. Metabolic Enzyme/Protease
  2. MMP
  3. Dnp-PYAYWMR

Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Dnp-PYAYWMR Chemical Structure

Dnp-PYAYWMR Chemical Structure

CAS No. : 135662-06-5

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Description

Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1].

IC50 & Target

MMP3[1]

Molecular Weight

1152.24

Formula

C54H65N13O14S

CAS No.
Sequence

{DNP}-Pro-Tyr-Ala-Tyr-Trp-Met-Arg

Sequence Shortening

{DNP}-PYAYWMR

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Dnp-PYAYWMR
Cat. No.:
HY-P2089
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