2. Peptides
  3. Peptide and Derivatives
  4. Inhibitors and Substrates
  5. Enzyme Substrates

Enzyme Substrates

Custom Peptide Synthesis

Enzyme Substrates (588):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P1002
    Suc-Leu-Leu-Val-Tyr-AMC 94367-21-2 99.57%
    Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate.
    Suc-Leu-Leu-Val-Tyr-AMC
  • HY-P0019A
    Z-Gly-Gly-Arg-AMC acetate 2070009-61-7 99.87%
    Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
    Z-Gly-Gly-Arg-AMC acetate
  • HY-136626
    Z-Ala-Ala-Asn-AMC 149697-16-5 99.47%
    Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC.
    Z-Ala-Ala-Asn-AMC
  • HY-P1003
    Ac-DEVD-AMC 169332-61-0 99.93%
    Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm.
    Ac-DEVD-AMC
  • HY-P2573
    Suc-AAPF-pNA 70967-97-4 99.87%
    Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils.
    Suc-AAPF-pNA
  • HY-P10398
    5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA
    5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA is a substrate for ADAMTS-4/ADAMTS-5, and can be used to detect ADAMTS-4 or ADAMTS-5 activity.
    5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA
  • HY-P10461
    Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp 1042405-14-0 99.65%
    Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1), and can be used for detection of proteinase 3 (PR3) activity.
    Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp
  • HY-P2618
    Pro-Phe-Arg-AMC acetate 2237216-30-5 99.49%
    Pro-Phe-Arg-AMC acetate is a peptide that can be used as the substrate of human glandular kallikrein 2 (hK2).
    Pro-Phe-Arg-AMC acetate
  • HY-134124
    Glutathione ethyl ester 92614-59-0
    Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense.
    Glutathione ethyl ester
  • HY-P2295
    Dabcyl-KTSAVLQSGFRKME-Edans TFA 99.75%
    Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection.
    Dabcyl-KTSAVLQSGFRKME-Edans TFA
  • HY-P4931
    Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 720710-69-0 99.87%
    Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1. (Ex/Em=325 nm/400 nm)
    Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2
  • HY-P1005
    Ac-DEVD-AFC 201608-14-2 98.62%
    Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm).
    Ac-DEVD-AFC
  • HY-P2171A
    CCP peptide TFA
    CCP peptide TFA is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide TFA functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).
    CCP peptide TFA
  • HY-W010991
    N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly 64967-39-1 99.59%
    N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a synthetic cromogenic substrate for angiotensin converting enzyme (ACE) determination.
    N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly
  • HY-P1169
    Ac-IETD-AFC 211990-57-7 99.91%
    Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B.
    Ac-IETD-AFC
  • HY-123053
    Z-Leu-Leu-Glu-AMC 348086-66-8 99.91%
    Z-Leu-Leu-Glu-AMC is a substrate peptide, and can be used for determination of postacidic-like hydrolysing activity of 20S proteasome
    Z-Leu-Leu-Glu-AMC
  • HY-P5438
    Srctide 99.93%
    Srctide is a biological active peptide. (This is a peptide substrate for many protein kinases, such as Blk, BTK, cKit, EPHA1, EPHB2, EPHB3, ERBB4, FAK, Flt3, IGF-1R, ITK, Lck, MET, MUSK, Ret, Src, TIE2, TrkB, VEGF-R1 (Flt-1) and VEGF-R2 (VEGFR2/KDR/Flk-1).)
    Srctide
  • HY-P4217
    Z-Gly-Pro-Arg-AMC hydrochloride 201928-42-9 98.60%
    Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity.
    Z-Gly-Pro-Arg-AMC hydrochloride
  • HY-P2237
    Boc-Leu-Gly-Arg-AMC 65147-09-3 98.61%
    Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays.
    Boc-Leu-Gly-Arg-AMC
  • HY-P1986
    Z-DEVD-AFC 1135416-11-3 98.95%
    Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity.
    Z-DEVD-AFC