2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Dofetilide-d4

Dofetilide-d4  (Synonyms: UK 68789 d4)

Cat. No.: HY-B0232S Purity: 99.25%
COA Handling Instructions

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Dofetilide-d4 is a deuterium labeled Dofetilide. Dofetilide is a class III antiarrhythmic agent.

For research use only. We do not sell to patients.

Dofetilide-d<sub>4</sub> Chemical Structure

Dofetilide-d4 Chemical Structure

CAS No. : 1189700-56-8

Size Price Stock Quantity
500 μg USD 150 In-stock
1 mg USD 280 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Dofetilide-d4:

Dofetilide-d4 Related Antibodies

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Description

Dofetilide-d4 is a deuterium labeled Dofetilide. Dofetilide is a class III antiarrhythmic agent.

Molecular Weight

445.59

Formula

C19H23D4N3O5S2
CAS No.
Unlabeled CAS

115256-11-6
Appearance

Solid

Color

White to off-white

SMILES

CS(=O)(NC1=CC=C(CCN(C)C([2H])([2H])C([2H])([2H])OC2=CC=C(NS(=O)(C)=O)C=C2)C=C1)=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (224.42 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 100 mg/mL (224.42 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2442 mL 11.2211 mL 22.4422 mL
5 mM 0.4488 mL 2.2442 mL 4.4884 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.2442 mL 11.2211 mL 22.4422 mL 56.1054 mL
5 mM 0.4488 mL 2.2442 mL 4.4884 mL 11.2211 mL
10 mM 0.2244 mL 1.1221 mL 2.2442 mL 5.6105 mL
15 mM 0.1496 mL 0.7481 mL 1.4961 mL 3.7404 mL
20 mM 0.1122 mL 0.5611 mL 1.1221 mL 2.8053 mL
25 mM 0.0898 mL 0.4488 mL 0.8977 mL 2.2442 mL
30 mM 0.0748 mL 0.3740 mL 0.7481 mL 1.8702 mL
40 mM 0.0561 mL 0.2805 mL 0.5611 mL 1.4026 mL
50 mM 0.0449 mL 0.2244 mL 0.4488 mL 1.1221 mL
60 mM 0.0374 mL 0.1870 mL 0.3740 mL 0.9351 mL
80 mM 0.0281 mL 0.1403 mL 0.2805 mL 0.7013 mL
100 mM 0.0224 mL 0.1122 mL 0.2244 mL 0.5611 mL
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Dofetilide-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dofetilide-d41189700-56-8UK 68789 d4Potassium ChannelKcsAantiarrhythmicInhibitorinhibitorinhibit

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