2. Others Anti-infection
  3. Isotope-Labeled Compounds HIV Reverse Transcriptase
  4. Doravirine-13C,d3

Doravirine-13C,d3  (Synonyms: MK-1439-13C,d3)

Cat. No.: HY-16767S1
Handling Instructions

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Doravirine-13C,d3 (MK-1439-13C,d3) is the deuterium labeled Doravirine (HY-16767). Doravirine (MK-1439) is a highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50s of 4.5 nM, 5.5 nM and 6.1 nM against the wild type and K103N and Y181C reverse transcriptase mutants, respectively.

For research use only. We do not sell to patients.

Doravirine-<sup>13</sup>C,d<sub>3</sub> Chemical Structure

Doravirine-13C,d3 Chemical Structure

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Other Forms of Doravirine-13C,d3:

Doravirine-13C,d3 Related Antibodies

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Description

Doravirine-13C,d3 (MK-1439-13C,d3) is the deuterium labeled Doravirine (HY-16767). Doravirine (MK-1439) is a highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50s of 4.5 nM, 5.5 nM and 6.1 nM against the wild type and K103N and Y181C reverse transcriptase mutants, respectively[1].

Molecular Weight

429.76

Formula

C1613CH8D3ClF3N5O3
Unlabeled CAS

1338225-97-0
SMILES

N#CC1=CC(OC2=C(C(F)(F)F)C=CN(CC(N3[13C]([2H])([2H])[2H])=NNC3=O)C2=O)=CC(Cl)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Doravirine-13C,d3 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Doravirine-13C,d3MK-1439-13C,d3Isotope-Labeled CompoundsHIVReverse TranscriptaseHuman immunodeficiency virusInhibitorinhibitorinhibit

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