2. Others Antibody-drug Conjugate/ADC Related
  3. Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)
  4. DOTAM-mono-acid

DOTAM-mono-acidis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-mono-acid can be used for conjugation of peptides and radionuclides.

For research use only. We do not sell to patients.

DOTAM-mono-acid Chemical Structure

DOTAM-mono-acid Chemical Structure

CAS No. : 913528-04-8

Size Price Stock Quantity
25 mg USD 316 In-stock
50 mg USD 490 In-stock
100 mg USD 790 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

DOTAM-mono-acid Related Antibodies

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Description

DOTAM-mono-acidis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-mono-acid can be used for conjugation of peptides and radionuclides.

IC50 & Target

RDC Bifunctional Chelator

 

Molecular Weight

401.46

Formula

C16H31N7O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CN1CCN(CCN(CCN(CC1)CC(N)=O)CC(N)=O)CC(N)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (311.36 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4909 mL 12.4545 mL 24.9091 mL
5 mM 0.4982 mL 2.4909 mL 4.9818 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4909 mL 12.4545 mL 24.9091 mL 62.2727 mL
5 mM 0.4982 mL 2.4909 mL 4.9818 mL 12.4545 mL
10 mM 0.2491 mL 1.2455 mL 2.4909 mL 6.2273 mL
15 mM 0.1661 mL 0.8303 mL 1.6606 mL 4.1515 mL
20 mM 0.1245 mL 0.6227 mL 1.2455 mL 3.1136 mL
25 mM 0.0996 mL 0.4982 mL 0.9964 mL 2.4909 mL
30 mM 0.0830 mL 0.4152 mL 0.8303 mL 2.0758 mL
40 mM 0.0623 mL 0.3114 mL 0.6227 mL 1.5568 mL
50 mM 0.0498 mL 0.2491 mL 0.4982 mL 1.2455 mL
60 mM 0.0415 mL 0.2076 mL 0.4152 mL 1.0379 mL
80 mM 0.0311 mL 0.1557 mL 0.3114 mL 0.7784 mL
100 mM 0.0249 mL 0.1245 mL 0.2491 mL 0.6227 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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DOTAM-mono-acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DOTAM-mono-acid913528-04-8Biochemical Assay ReagentsRadionuclide-Drug Conjugates (RDCs)Inhibitorinhibitorinhibit

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