DPQ hydrochloride (Synonyms: 6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine hydrochloride)

Cat. No.: HY-W424851: FAQs
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DPQ hydrochloride (6, 7-dimethoxy-2 -(1-piperazinyl)-4-quinazolinamine hydrochloride) is a PARP1 inhibitor, with IC₅₀ value of 40 nM. DPQ hydrochloride has anti-inflammatory and antiviral activity. DPQ hydrochloride is used to study acute lung injury.

For research use only. We do not sell to patients.

DPQ hydrochloride Chemical Structure

CAS No. : 84050-22-6

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Other In-stock Forms of DPQ hydrochloride:

DPQ

Other Forms of DPQ hydrochloride:

DPQ In-stock
2-PADQZ Get quote

1 Publications Citing Use of MCE DPQ hydrochloride

•Sci Immunol. 2024 Jun 14;9(96):eadj5465. [Abstract]

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•Related Small Molecules:

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View All PARP Isoform Specific Products:

View All Isoforms

PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

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Purity & Documentation
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Description	DPQ hydrochloride (6, 7-dimethoxy-2 -(1-piperazinyl)-4-quinazolinamine hydrochloride) is a PARP1 inhibitor, with IC₅₀ value of 40 nM. DPQ hydrochloride has anti-inflammatory and antiviral activity. DPQ hydrochloride is used to study acute lung injury^[1]^[2].
Molecular Weight	325.79
Formula	C₁₄H₂₀ClN₅O₂
CAS No.	84050-22-6
SMILES	NC1=C2C=C(OC)C(OC)=CC2=NC(N3CCNCC3)=N1.[H]Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Wang G, et al. PARP-1 inhibitor, DPQ, attenuates LPS-induced acute lung injury through inhibiting NF-κB-mediated inflammatory response. PLoS One. 2013 Nov 21;8(11):e79757. [Content Brief] [2]. Bottini A, et al. Targeting Influenza A Virus RNA Promoter. Chem Biol Drug Des. 2015 Oct;86(4):663-73. [Content Brief]

DPQ hydrochloride Related Classifications

Inflammation/Immunology Infection

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DPQ84050-22-66,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinaminePARPpoly ADP ribose polymeraseInhibitorAnti-inflammationAntiviralAcute lung injuryinhibitorinhibit

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