2. Cytoskeleton
  3. Dynamin
  4. Drp1-IN-1

Drp1-IN-1 (comp A-7) is a dynamin-1-like protein (Drp1) inhibitor, with an IC50 of 0.91 μM.

For research use only. We do not sell to patients.

Drp1-IN-1 Chemical Structure

Drp1-IN-1 Chemical Structure

CAS No. : 2247733-08-8

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1 mg USD 380 In-stock
5 mg USD 950 In-stock
10 mg USD 1550 In-stock
25 mg USD 2800 In-stock
50 mg USD 4500 In-stock
100 mg USD 6800 In-stock
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Based on 1 publication(s) in Google Scholar

Drp1-IN-1 Related Antibodies

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Description

Drp1-IN-1 (comp A-7) is a dynamin-1-like protein (Drp1) inhibitor, with an IC50 of 0.91 μM[1].

Molecular Weight

448.54

Formula

C22H24N8OS
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C1=CC(C)=CN1CC2=CSC(N3CCCCC3)=N2)NC4=CC=C(C5=NN=NN5)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (222.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2295 mL 11.1473 mL 22.2946 mL
5 mM 0.4459 mL 2.2295 mL 4.4589 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2295 mL 11.1473 mL 22.2946 mL 55.7364 mL
5 mM 0.4459 mL 2.2295 mL 4.4589 mL 11.1473 mL
10 mM 0.2229 mL 1.1147 mL 2.2295 mL 5.5736 mL
15 mM 0.1486 mL 0.7432 mL 1.4863 mL 3.7158 mL
20 mM 0.1115 mL 0.5574 mL 1.1147 mL 2.7868 mL
25 mM 0.0892 mL 0.4459 mL 0.8918 mL 2.2295 mL
30 mM 0.0743 mL 0.3716 mL 0.7432 mL 1.8579 mL
40 mM 0.0557 mL 0.2787 mL 0.5574 mL 1.3934 mL
50 mM 0.0446 mL 0.2229 mL 0.4459 mL 1.1147 mL
60 mM 0.0372 mL 0.1858 mL 0.3716 mL 0.9289 mL
80 mM 0.0279 mL 0.1393 mL 0.2787 mL 0.6967 mL
100 mM 0.0223 mL 0.1115 mL 0.2229 mL 0.5574 mL
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Drp1-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Drp1-IN-12247733-08-8DynaminInhibitorinhibitorinhibit

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