2. Neuronal Signaling
  3. Monoamine Oxidase
  4. (E)-CHBO4

(E)-CHBO4 is a MAO-B inhibitor, with an IC50 of 0.023 μM, and can be used for research on the treatment of Parkinson's disease.

For research use only. We do not sell to patients.

(E)-CHBO4 Chemical Structure

(E)-CHBO4 Chemical Structure

CAS No. : 126473-61-8

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Based on 1 publication(s) in Google Scholar

(E)-CHBO4 Related Antibodies

Top Publications Citing Use of Products

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MAO-A MAO-B

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Description

(E)-CHBO4 is a MAO-B inhibitor, with an IC50 of 0.023 μM, and can be used for research on the treatment of Parkinson's disease[1].

IC50 & Target

MAO-B

0.023 μM (IC50)

Molecular Weight

305.14

Formula

C15H10BrFO
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

FC(C=C1)=CC=C1/C=C/C(C2=CC=C(C=C2)Br)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (163.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2772 mL 16.3859 mL 32.7718 mL
5 mM 0.6554 mL 3.2772 mL 6.5544 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2772 mL 16.3859 mL 32.7718 mL 81.9296 mL
5 mM 0.6554 mL 3.2772 mL 6.5544 mL 16.3859 mL
10 mM 0.3277 mL 1.6386 mL 3.2772 mL 8.1930 mL
15 mM 0.2185 mL 1.0924 mL 2.1848 mL 5.4620 mL
20 mM 0.1639 mL 0.8193 mL 1.6386 mL 4.0965 mL
25 mM 0.1311 mL 0.6554 mL 1.3109 mL 3.2772 mL
30 mM 0.1092 mL 0.5462 mL 1.0924 mL 2.7310 mL
40 mM 0.0819 mL 0.4096 mL 0.8193 mL 2.0482 mL
50 mM 0.0655 mL 0.3277 mL 0.6554 mL 1.6386 mL
60 mM 0.0546 mL 0.2731 mL 0.5462 mL 1.3655 mL
80 mM 0.0410 mL 0.2048 mL 0.4096 mL 1.0241 mL
100 mM 0.0328 mL 0.1639 mL 0.3277 mL 0.8193 mL
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(E)-CHBO4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E)-CHBO4126473-61-8Monoamine OxidaseMAOMAO-BParkinsonInhibitorinhibitorinhibit

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