2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. RAR/RXR
  4. (E)-XS-060

(E)-XS-060 is an isomer of XS-060. XS-060 is a RXRα antagonist. XS-060 inhibits pRXRα-PLK1 interaction. XS-060 induces RXRα-dependent mitotic arrest. XS-060 exhibits good antitumor activity against breast cancer, lung adenocarcinoma, and liver cancer.

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(E)-XS-060 Chemical Structure

(E)-XS-060 Chemical Structure

CAS No. : 2787626-06-4

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(E)-XS-060 Related Antibodies

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Description

(E)-XS-060 is an isomer of XS-060. XS-060 is a RXRα antagonist. XS-060 inhibits pRXRα-PLK1 interaction. XS-060 induces RXRα-dependent mitotic arrest. XS-060 exhibits good antitumor activity against breast cancer, lung adenocarcinoma, and liver cancer[1].

IC50 & Target[1]

RXR α

 

Molecular Weight

334.37

Formula

C20H18N2O3
CAS No.
SMILES

COC(C=C1)=CC=C1CC(N/N=C/C2=C(O)C=CC3=C2C=CC=C3)=O
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Purity & Documentation
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(E)-XS-060 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E)-XS-0602787626-06-4RAR/RXRRetinoic acid receptorsRetinoid X receptorsantitumobreast cancerlung adenocarcinomaand liver cancerInhibitorinhibitorinhibit

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