2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Pomalidomide-C2-NH2

Pomalidomide-C2-NH2  (Synonyms: Cereblon Ligand-Linker Conjugates 15)

Cat. No.: HY-128846
Handling Instructions

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Pomalidomide-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology.

For research use only. We do not sell to patients.

Pomalidomide-C2-NH2 Chemical Structure

Pomalidomide-C2-NH2 Chemical Structure

CAS No. : 1957235-66-3

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Based on 1 publication(s) in Google Scholar

Other Forms of Pomalidomide-C2-NH2:

Pomalidomide-C2-NH2 Related Antibodies

Top Publications Citing Use of Products

View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Description

Pomalidomide-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology.

IC50 & Target

Cereblon

 

Molecular Weight

316.31

Formula

C15H16N4O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(NC1=O)CCC1N(C2=O)C(C3=C2C(NCCN)=CC=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Pomalidomide-C2-NH2 Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide-C2-NH21957235-66-3Cereblon Ligand-Linker Conjugates 15E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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