1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. E3 Ligase Ligand-linker Conjugate 149

E3 Ligase Ligand-linker Conjugate 149 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 149 can be used to synthesize Setidegrasib (HY-148273).

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E3 Ligase Ligand-linker Conjugate 149 Chemical Structure

E3 Ligase Ligand-linker Conjugate 149 Chemical Structure

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Description

E3 Ligase Ligand-linker Conjugate 149 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 149 can be used to synthesize Setidegrasib (HY-148273)[1].

Molecular Weight

604.72

Formula

C31H36N6O5S

SMILES

OCC1=CC=C(C(N=N2)=CN2[C@@H](C(C)C)C(N(C[C@@H]3O)[C@@H](C3)C(N[C@H](C4=CC=C(C(SC=N5)=C5C)C=C4)CO)=O)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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E3 Ligase Ligand-linker Conjugate 149 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
E3 Ligase Ligand-linker Conjugate 149
Cat. No.:
HY-168701
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