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  5. Ebiratide

Ebiratide (HOE-427 free base) is a synthesized ACTH derivative, which acts directly on the central nervous system and exhibits memory-enhancing efficacy.

For research use only. We do not sell to patients.

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Ebiratide Chemical Structure

Ebiratide Chemical Structure

CAS No. : 105611-68-5

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Ebiratide Related Antibodies

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Description

Ebiratide (HOE-427 free base) is a synthesized ACTH derivative, which acts directly on the central nervous system and exhibits memory-enhancing efficacy[1].

In Vivo

Ebiratide (0.1-30 μg/kg, s.c., single dose) exhibits neuroprotective efficacy in electoconvulsive shock and Scopolamine (HY-N0296)-induced memory impairment in mice model, exhibits anti-amnestic efficacy[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Electoconvulsive shock induced and Scopolamine (HY-N0296)-induced memory impairment in NMRI mice[1]
Dosage: 0.1-30 μg/kg
Administration: s.c., single dose
Result: Reduced the retention latency.
Molecular Weight

996.23

Formula

C48H73N11O10S
CAS No.
Sequence

{Met(O2)}-Glu-His-Phe-{d-Lys}-{Phe-NH(CH2)8NH2}
Sequence Shortening

{Met(O2)}-EHF-{d-Lys}-{Phe-NH(CH2)8NH2}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ebiratide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ebiratide105611-68-5HOE-427HOE427HOE 427OthersAlzheimer's Diseasewistar ratsNMRI miceanti-amnesticInhibitorinhibitorinhibit

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