EBOV/MARV-IN-2

Cat. No.: HY-146813: FAQs
Data Sheet Handling Instructions

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EBOV/MARV-IN-2 (compound 13) is an Ebolavirus (EBOV, IC₅₀=0.9 μM) and Marburg virus (MARV, IC₅₀=2.7 μM) inhibitor.

For research use only. We do not sell to patients.

EBOV/MARV-IN-2 Chemical Structure

CAS No. : 2687244-84-2

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EBOV MARV ZEBOV

Biological Activity
Purity & Documentation
References
Customer Review

Description

EBOV/MARV-IN-2 (compound 13) is an Ebolavirus (EBOV, IC₅₀=0.9 μM) and Marburg virus (MARV, IC₅₀=2.7 μM) inhibitor^[1].

IC₅₀ & Target

EBOV

MARV

Cellular Effect

Cell Line	Type	Value	Description	References
A549	CC₅₀	> 100 μM Compound: 13	Cytotoxicity against human A549 cells assessed as reduction in cell viability by Celltiter-Glo assay Cytotoxicity against human A549 cells assessed as reduction in cell viability by Celltiter-Glo assay	[PMID: 32707357]

Molecular Weight

444.52

Formula

C₂₇H₂₈N₂O₄

CAS No.

2687244-84-2

SMILES

CC1=C(C(OC2=CC(OCC(CNCCC3=CC=NC=C3)O)=CC=C21)=O)CC4=CC=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gao Y, et al. Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein. Eur J Med Chem. 2020 Oct 15;204:112595. [Content Brief]

EBOV/MARV-IN-2 Related Classifications

Infection

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EBOV/MARV-IN-22687244-84-2FilovirusEbolavirusMarburg virusInhibitorinhibitorinhibit

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