2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Eburicoic acid

Eburicoic acid protects the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms. And Eburicoic acid has antidiabetic and antihyperlipidemic effects.

For research use only. We do not sell to patients.

Eburicoic acid Chemical Structure

Eburicoic acid Chemical Structure

CAS No. : 560-66-7

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5 mg In-stock
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Based on 1 publication(s) in Google Scholar

Eburicoic acid Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Eburicoic acid protects the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms[1]. And Eburicoic acid has antidiabetic and antihyperlipidemic effects[2].

Cellular Effect
Cell Line Type Value Description References
HL-60 IC50
25 μM
Compound: 3
Cytotoxicity against human HL60 cells after 96 hrs by MTT assay
Cytotoxicity against human HL60 cells after 96 hrs by MTT assay
[PMID: 15620242]
MCF7 IC50
> 100 μM
Compound: 21
Cytotoxicity against human MCF7 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human MCF7 cells incubated for 24 hrs by MTT assay
[PMID: 31891260]
SW480 IC50
> 100 μM
Compound: 21
Cytotoxicity against human SW480 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human SW480 cells incubated for 24 hrs by MTT assay
[PMID: 31891260]
U-251 IC50
> 100 μM
Compound: 21
Cytotoxicity against human U251 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human U251 cells incubated for 24 hrs by MTT assay
[PMID: 31891260]
Molecular Weight

470.73

Formula

C31H50O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]12C3=C(CC[C@@]1([C@@](CC2)([H])[C@H](C(O)=O)CCC(C(C)C)=C)C)[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC3)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 0.5 mg/mL (1.06 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1244 mL 10.6218 mL 21.2436 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1244 mL 10.6218 mL 21.2436 mL 53.1090 mL
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Eburicoic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eburicoic acid560-66-7Reactive Oxygen SpeciesInhibitorinhibitorinhibit

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