1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. eeAChE/eqBuChE-IN-1

eeAChE/eqBuChE-IN-1 (compound 3F) is a reversible dual eeAChE/eqBuChE inhibitor with IC50s of 1.3?μM and 0.81?μM, respectively. eeAChE/eqBuChE-IN-1 exhibits anti-inflammatory activity. eeAChE/eqBuChE-IN-1 also shows neuroprotective effect on Aβ25-35-induced PC12 cell injury.

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eeAChE/eqBuChE-IN-1 Chemical Structure

eeAChE/eqBuChE-IN-1 Chemical Structure

CAS No. : 2921654-26-2

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Description

eeAChE/eqBuChE-IN-1 (compound 3F) is a reversible dual eeAChE/eqBuChE inhibitor with IC50s of 1.3?μM and 0.81?μM, respectively. eeAChE/eqBuChE-IN-1 exhibits anti-inflammatory activity. eeAChE/eqBuChE-IN-1 also shows neuroprotective effect on Aβ25-35-induced PC12 cell injury[1].

IC50 & Target

IC50: 1.3?μM (eeAChE) and 0.81?μM (eqBuChE)[1]

Molecular Weight

244.29

Formula

C14H16N2O2

CAS No.
SMILES

O=C(OC1=C2C=CC=NC2=CC=C1)N(CC)CC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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eeAChE/eqBuChE-IN-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
eeAChE/eqBuChE-IN-1
Cat. No.:
HY-157394
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