2. Anti-infection
  3. Fungal
  4. Efungumab

Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC).

For research use only. We do not sell to patients.

CAS No. : 762260-74-2

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Efungumab Related Antibodies

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Description

Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC)[1].

Isotype

scFv-heavy-kappa
Species

Humanized
In Vivo

Efungumab (2 mg/kg, i.p., daily for 3 days) significantly decreases mean organ colony counts and increases negative liver biopsies for many of the isolates in CD1 mice models of disseminated c. albicans disease[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CD1 mice models of disseminated c. albicans disease[2]
Dosage: 2 mg/kg, daily for 3 days
Administration: Intraperitoneal injection (i.p.)
Result: Decreased mean organ colony counts and increased negative liver biopsies for many of the isolates.
Clinical Trial
CAS No.
SMILES

[Efungumab]
Storage

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Format
  • scFv-heavy-kappa
Purity & Documentation
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Efungumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Efungumab762260-74-2Fungalmonoclonal antibodyantifungalinvasive candidiasis (IC)Inhibitorinhibitorinhibit

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