2. Others
  3. Others
  4. EG-2184

EG-2184 is a Pannexin-1 channel inhibitor. EG-2184 can be used in opioid withdrawal related research.

For research use only. We do not sell to patients.

EG-2184 Chemical Structure

EG-2184 Chemical Structure

CAS No. : 2770297-66-8

Size Price Stock Quantity
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

EG-2184 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

EG-2184 is a Pannexin-1 channel inhibitor. EG-2184 can be used in opioid withdrawal related research[1].

IC50 & Target

Panx1

 

Molecular Weight

407.37

Formula

C15H19F6NO3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=C(C(C(F)(F)F)(C(F)(F)F)O)C=C1)(N(CCC)CCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (245.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4548 mL 12.2739 mL 24.5477 mL
5 mM 0.4910 mL 2.4548 mL 4.9095 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4548 mL 12.2739 mL 24.5477 mL 61.3693 mL
5 mM 0.4910 mL 2.4548 mL 4.9095 mL 12.2739 mL
10 mM 0.2455 mL 1.2274 mL 2.4548 mL 6.1369 mL
15 mM 0.1637 mL 0.8183 mL 1.6365 mL 4.0913 mL
20 mM 0.1227 mL 0.6137 mL 1.2274 mL 3.0685 mL
25 mM 0.0982 mL 0.4910 mL 0.9819 mL 2.4548 mL
30 mM 0.0818 mL 0.4091 mL 0.8183 mL 2.0456 mL
40 mM 0.0614 mL 0.3068 mL 0.6137 mL 1.5342 mL
50 mM 0.0491 mL 0.2455 mL 0.4910 mL 1.2274 mL
60 mM 0.0409 mL 0.2046 mL 0.4091 mL 1.0228 mL
80 mM 0.0307 mL 0.1534 mL 0.3068 mL 0.7671 mL
100 mM 0.0245 mL 0.1227 mL 0.2455 mL 0.6137 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

EG-2184 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EG-21842770297-66-8EG2184EG 2184OthersnorepinephrineOpioid withdrawalmiceInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
EG-2184
Cat. No.:
HY-163905
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (251 KB) Français - FR (251 KB) Deutsch - DE (251 KB) Norwegian - NO (251 KB) Español - ES (251 KB) Swedish - SV (251 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.