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  3. Reverse Transcriptase HBV HIV
  4. Emtricitabine triphosphate tetrasodium salt

Emtricitabine triphosphate tetrasodium salt  (Synonyms: (-)-Emtricitabine triphosphate tetrasodium salt)

Cat. No.: HY-131596B Purity: 99.06%
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Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However，Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427)，a nucleoside reverse transcriptase inhibitor，targeting to HIV and HBV.

For research use only. We do not sell to patients.

Emtricitabine triphosphate tetrasodium salt Chemical Structure

Emtricitabine triphosphate tetrasodium salt Chemical Structure

CAS No. : 1188407-46-6

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10 mg USD 800 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However，Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427)，a nucleoside reverse transcriptase inhibitor，targeting to HIV and HBV[1].

Molecular Weight

575.11

Formula

C8H9FN3Na4O12P3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])OC[C@@H]1O[C@H](N2C=C(F)C(N)=NC2=O)CS1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (217.35 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7388 mL 8.6940 mL 17.3880 mL
5 mM 0.3478 mL 1.7388 mL 3.4776 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7388 mL 8.6940 mL 17.3880 mL 43.4699 mL
5 mM 0.3478 mL 1.7388 mL 3.4776 mL 8.6940 mL
10 mM 0.1739 mL 0.8694 mL 1.7388 mL 4.3470 mL
15 mM 0.1159 mL 0.5796 mL 1.1592 mL 2.8980 mL
20 mM 0.0869 mL 0.4347 mL 0.8694 mL 2.1735 mL
25 mM 0.0696 mL 0.3478 mL 0.6955 mL 1.7388 mL
30 mM 0.0580 mL 0.2898 mL 0.5796 mL 1.4490 mL
40 mM 0.0435 mL 0.2173 mL 0.4347 mL 1.0867 mL
50 mM 0.0348 mL 0.1739 mL 0.3478 mL 0.8694 mL
60 mM 0.0290 mL 0.1449 mL 0.2898 mL 0.7245 mL
80 mM 0.0217 mL 0.1087 mL 0.2173 mL 0.5434 mL
100 mM 0.0174 mL 0.0869 mL 0.1739 mL 0.4347 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Emtricitabine triphosphate tetrasodium salt Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Emtricitabine triphosphate tetrasodium1188407-46-6(-)-Emtricitabine triphosphate tetrasodiumReverse TranscriptaseHBVHIVHepatitis B virusHuman immunodeficiency virusInhibitorinhibitorinhibit

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