2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation
  3. ADC Antibody Nectin-4
  4. Enfortumab

Enfortumab is a humanized derived anti-Nectin-4 antibody that can be conjugated with the highly efficient microtubule disruptor MMAE (HY-15162) to generate the antibody drug conjugate (ADC) Enfortumab vedotin (HY-P99016A). Enfortumab can be used for the study of locally advanced and metastatic urothelial carcinoma.

For research use only. We do not sell to patients.

CAS No. : 1448664-46-7

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Based on 1 publication(s) in Google Scholar

Other Forms of Enfortumab:

Enfortumab Related Antibodies

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Description

Enfortumab is a humanized derived anti-Nectin-4 antibody that can be conjugated with the highly efficient microtubule disruptor MMAE (HY-15162) to generate the antibody drug conjugate (ADC) Enfortumab vedotin (HY-P99016A). Enfortumab can be used for the study of locally advanced and metastatic urothelial carcinoma[1][2].
Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Human
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Enfortumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized Human Nectin-4 His can bind Enfortumab. The EC50 for this effect is 3.846 ng/mL.
Purity & Documentation

Purity: 99.90%

SDS (251 KB)

COA (231 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Enfortumab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Enfortumab1448664-46-7ADC AntibodyNectin-4Anti-Nectin-4 antibodyADCurothelial carcinomaInhibitorinhibitorinhibit

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