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  6. Entadamide A

Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].

For research use only. We do not sell to patients.

Entadamide A Chemical Structure

Entadamide A Chemical Structure

CAS No. : 100477-88-1

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Description

Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].

Molecular Weight

161.22

Formula

C6H11NO2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CS/C=C/C(NCCO)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (620.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.2027 mL 31.0135 mL 62.0270 mL
5 mM 1.2405 mL 6.2027 mL 12.4054 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.2027 mL 31.0135 mL 62.0270 mL 155.0676 mL
5 mM 1.2405 mL 6.2027 mL 12.4054 mL 31.0135 mL
10 mM 0.6203 mL 3.1014 mL 6.2027 mL 15.5068 mL
15 mM 0.4135 mL 2.0676 mL 4.1351 mL 10.3378 mL
20 mM 0.3101 mL 1.5507 mL 3.1014 mL 7.7534 mL
25 mM 0.2481 mL 1.2405 mL 2.4811 mL 6.2027 mL
30 mM 0.2068 mL 1.0338 mL 2.0676 mL 5.1689 mL
40 mM 0.1551 mL 0.7753 mL 1.5507 mL 3.8767 mL
50 mM 0.1241 mL 0.6203 mL 1.2405 mL 3.1014 mL
60 mM 0.1034 mL 0.5169 mL 1.0338 mL 2.5845 mL
80 mM 0.0775 mL 0.3877 mL 0.7753 mL 1.9383 mL
100 mM 0.0620 mL 0.3101 mL 0.6203 mL 1.5507 mL
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Entadamide A Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Entadamide A100477-88-1Otherstryptophan derivativeHIVindolamine 2,3-dioxygenaseInhibitorinhibitorinhibit

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