2. Autophagy Others Vitamin D Related/Nuclear Receptor
  3. Androgen Receptor Autophagy Isotope-Labeled Compounds
  4. Enzalutamide carboxylic acid-d6

Enzalutamide carboxylic acid-d6  (Synonyms: MDV3100 carboxylic acid-d6)

Cat. No.: HY-70002BS Purity: 98.99%
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Enzalutamide carboxylic acid-d6 is the deuterium labeled Enzalutamide carboxylic acid (MDV3100 carboxylic acid). Enzalutamide carboxylic acid is an inactive metabolite of Enzalutamide[1].

For research use only. We do not sell to patients.

Enzalutamide carboxylic acid-d<sub>6</sub> Chemical Structure

Enzalutamide carboxylic acid-d6 Chemical Structure

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1 mg USD 370 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Enzalutamide carboxylic acid-d6:

Enzalutamide carboxylic acid-d6 Related Antibodies

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Description

Enzalutamide carboxylic acid-d6 is the deuterium labeled Enzalutamide carboxylic acid (MDV3100 carboxylic acid). Enzalutamide carboxylic acid is an inactive metabolite of Enzalutamide[1].

Molecular Weight

457.43

Formula

C20H7D6F4N3O3S
Unlabeled CAS

1242137-15-0
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3)=S)C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C2=O)C=C1F
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (273.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 125 mg/mL (273.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1861 mL 10.9306 mL 21.8613 mL
5 mM 0.4372 mL 2.1861 mL 4.3723 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.1861 mL 10.9306 mL 21.8613 mL 54.6532 mL
5 mM 0.4372 mL 2.1861 mL 4.3723 mL 10.9306 mL
10 mM 0.2186 mL 1.0931 mL 2.1861 mL 5.4653 mL
15 mM 0.1457 mL 0.7287 mL 1.4574 mL 3.6435 mL
20 mM 0.1093 mL 0.5465 mL 1.0931 mL 2.7327 mL
25 mM 0.0874 mL 0.4372 mL 0.8745 mL 2.1861 mL
30 mM 0.0729 mL 0.3644 mL 0.7287 mL 1.8218 mL
40 mM 0.0547 mL 0.2733 mL 0.5465 mL 1.3663 mL
50 mM 0.0437 mL 0.2186 mL 0.4372 mL 1.0931 mL
60 mM 0.0364 mL 0.1822 mL 0.3644 mL 0.9109 mL
80 mM 0.0273 mL 0.1366 mL 0.2733 mL 0.6832 mL
100 mM 0.0219 mL 0.1093 mL 0.2186 mL 0.5465 mL
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Enzalutamide carboxylic acid-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Enzalutamide carboxylic acid-d6MDV3100 carboxylic acid-d6Androgen ReceptorAutophagyIsotope-Labeled CompoundsmetaboliteinactivedeuteriumInhibitorinhibitorinhibit

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